The clinician's goal is to identify and diagnose malignancy in periocular lesions. 15-20% of periocular lesions are malignant. 2% of lesions that appear benign are found to be malignant when biopsied. The most frequent malignant eyelid lesions are (in order of frequency) basal cell carcinoma, squamous cell carcinoma, sebaceous adenocarcinoma, and malignant melanoma.
When evaluating an eyelid lesion, the easiest clue for malignancy is the loss of eyelashes (madarosis) over the tumor. Other features of malignancy include non-tender, irregular borders, and ulceration. The following serves as a brief review of common eyelid lesions, both benign and malignant.
BASAL CELL CARCINOMA: 90% of eyelid malignancy; 0.0028-0.1% metastasis
SQUAMOUS CELL CARCINOMA: 5% of eyelid malignancy; 0.23-2.4% metastasis
SEBACEOUS ADENOCARCINOMA: 1-5% of eyelid malignancy; 14-25% metastasis
MALIGNANT MELANOMA: less than 1% of eyelid malignancy; 50-100% 5-year survival rate
EYESTHETICA
Oculofacial and Cosmetic Surgery Associates
Steven C. Dresner, M.D. www.DrDresner.com
Michael A. Burnstine, M.D. www.DrBurnstine.com
Melanie Ho Erb, M.D.
Santa Monica Pasadena Torrance Downtown LA
310 453-1763 626 564-0004 310 530-9482 213 482-3467